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Contraindicated (1)pentobarbital will minimize the level or result of elbasvir/grazoprevir by influencing hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will minimize the extent or effect of conjugated estrogens by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.pentobarbital will decrease the level or result of